agammaglobulinemia 7

An agammaglobulinemia that has_material_basis_in homozygous mutation in the PIK3R1 gene on chromosome 5q13.

Signs and symptoms

• Recurrent infections
• Erythema nodosum
• Decreased total neutrophil count
• Reduced total natural killer cell count
• Panhypogammaglobulinemia
• Agammaglobulinemia
• Recurrent respiratory infections
• Abnormal T cell morphology