alpha-2-plasmin inhibitor deficiency

A hemorrhagic disease that has_material_basis_in mutation in the PLI gene. It is characterized by a hemorrhagic tendency presenting from childhood with prolonged bleeding and ecchymoses following minor trauma and spontaneous bleeding episodes.

Signs and symptoms

• Hemothorax
• Bruising susceptibility
• Joint hemorrhage
• Persistent bleeding after trauma

Also known as: antiplasmin defiency; plasmin inhibitor deficiency