Conditions / Syndrome
alpha-thalassemia myelodysplasia syndrome
info · Syndrome
A syndrome characterized by acquired alpha-thalassemia in association with a multilineage myelodysplasia that has_material_basis_in somatic mutation in the ATRX gene on chromosome Xq21.1.
Signs and symptoms
- Reduced alpha/beta synthesis ratio
- Hypochromic microcytic anemia
- HbH hemoglobin
- Myelodysplasia
Also known as: ATMDS; acquired HbH disease; acquired hemoglobin H disease; alpha-thalassemia-myelodysplastic syndrome