Conditions / Genetic
amyotrophic lateral sclerosis type 1
info · Genetic · ICD-10: G12.2
An amyotrophic lateral sclerosis that has_material_basis_in mutation in the SOD1 gene on chromosome 21. The most common type of familial ALS.
Signs and symptoms
- Skeletal muscle atrophy
- Dysphagia
- Degeneration of anterior horn cells
- Dysarthria
- Muscle spasm
- Fasciculations
- Sleep apnea
- Amyotrophic lateral sclerosis
- Pseudobulbar paralysis
- Muscle weakness
Also known as: ALS1; amyotrophic lateral sclerosis 1