antiphospholipid syndrome

An autoimmune disease that is characterized by recurrent venous or arterial thrombosis and/or fetal losses associated with characteristic elevated levels of antibodies directed against membrane anionic phospholipids (anticardiolipin).

Signs and symptoms

• Central retinal artery occlusion
• Retinal vasculitis
• Visual loss
• Retinal detachment
• Iritis
• Arterial thrombosis
• Keratitis
• Lupus anticoagulant
• Vitritis
• Scleritis

Also known as: APS; antiphospholipid antibody syndrome