aortic valve disease 1

A bicuspid aortic valve disease that has_material_basis_in heterozygous mutation in the NOTCH1 gene on chromosome 9q34.

Signs and symptoms

• Aortic valve calcification
• Bicuspid aortic valve
• Aortic valve stenosis
• Ventricular septal defect
• Double outlet right ventricle
• Mitral stenosis
• Mitral atresia
• Tetralogy of Fallot