arterial calcification of infancy

A vascular disease that is characterized by generalized calcification of the arterial internal elastic lamina, leading to rupture of the lamina and occlusive changes in the tunica intima with stenosis and decreased elasticity of the vessel wall.

Signs and symptoms

• Generalized arterial calcification
• Cardiomegaly
• Periarticular calcification
• Abdominal aortic calcification
• Carotid artery calcification
• Congestive heart failure
• Fetal distress
• Renal artery stenosis
• Dilated cardiomyopathy
• Cardiogenic shock

Also known as: generalized arterial calcification of infancy; idiopathic infantile arterial calcification; infantile arteriosclerosis