Conditions / Genetic

asphyxiating thoracic dystrophy 5

info · Genetic · ICD-10: Q77.2

An asphyxiating thoracic dystrophy that has_material_basis_in homozygous mutation in the WDR19 gene on chromosome 4p14.

Signs and symptoms

  • Chronic tubulointerstitial nephritis
  • Stage 5 chronic kidney disease
  • Metaphyseal widening
  • Rhizomelia
  • Short foot
  • Brachydactyly
  • Inguinal hernia
  • Renal hypoplasia
  • Short stature
  • Hepatomegaly

Also known as: ATD5; SRTD5; short-rib thoracic dysplasia 5 with or without polydactyly