Conditions / Genetic

autoimmune lymphoproliferative syndrome type 2A

info · Genetic · ICD-10: D47.9

An autoimmune lymphoproliferative syndrome that has_material_basis_in mutation in the CASP10 gene.

Signs and symptoms

  • Autoimmune hemolytic anemia
  • Hepatomegaly
  • Lymphadenopathy
  • Splenomegaly
  • Elevated erythrocyte sedimentation rate
  • Increased double-negative T cell number
  • Rheumatoid factor positive
  • Coombs-positive hemolytic anemia
  • Iron deficiency anemia
  • Antineutrophil antibody positivity

Also known as: ALPS2A; autoimmune lymphoproliferative syndrome type IIA