autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1

info · Genetic · ICD-10: F01.1

A CADASIL characterized by migraine, strokes, and white matter lesions that has_material_basis_in heterozygous mutation in the NOTCH3 gene on chromosome 19p13.

Signs and symptoms

Abulia
Personality changes
Memory impairment
Perseverative thought
Leukoencephalopathy
Psychosis
Stroke
Lacunar stroke
Migraine
Hemiparesis

Also known as: CADASIL 1