autosomal dominant hypophosphatemic rickets

A rickets characterized by low levels of serum phosphate and elevated levels of ALP and phosphaturia and that has_material_basis_in autosomal dominant inheritance.

Signs and symptoms

• Abnormality of the dentition
• Bone pain
• Generalized muscle weakness
• Short stature
• Elevated circulating alkaline phosphatase concentration
• Rickets
• Abnormality of the lower limb
• Renal phosphate wasting
• Osteomalacia
• Hypophosphatemic rickets