autosomal dominant intellectual developmental disorder 65

An autosomal dominant intellectual developmental disorder characterized by delayed motor and speech acquisition, variably impaired intellectual development, and behavioral abnormalities that has_material_basis_in heterozygous mutation in the KDM4B gene on chro

An autosomal dominant intellectual developmental disorder characterized by delayed motor and speech acquisition, variably impaired intellectual development, and behavioral abnormalities that has_material_basis_in heterozygous mutation in the KDM4B gene on chromosome 19p13.

Signs and symptoms

• Intellectual disability
• Delayed speech and language development
• Global developmental delay
• Hypotonia
• Agenesis of corpus callosum
• Dysgenesis of the hippocampus
• Delayed gross motor development
• Delayed fine motor development
• Aggressive behavior
• Attention deficit hyperactivity disorder