autosomal dominant thrombophilia due to protein S deficiency

info · Genetic

A protein S deficiency characterized by reduced serum protein S levels and recurrent venous thrombosis that has_material_basis_in heterozygous mutation in the PROS1 gene on chromosome 3q11.1.

Signs and symptoms

Arterial thrombosis
Purpura
Hypercoagulability
Superficial thrombophlebitis
Warfarin-induced skin necrosis
Reduced protein S activity
Cerebral venous thrombosis
Pulmonary embolism

Also known as: THPH5