Conditions / Urinary
autosomal dominant tubulointerstitial kidney disease 4
info · Urinary
An autosomal dominant tubulointerstitial kidney disease characterized by early-onset anemia and increased serum uric acid with a bland urinalysis and without proteinuria that has_material_basis_in heterozygous mutation in the renin gene on chromosome 1q32.
Signs and symptoms
- Renal hypoplasia
- Tubulointerstitial fibrosis
- Anemia
- Focal segmental glomerulosclerosis
- Hyperechogenic kidneys
- Proteinuria
- Renal tubular atrophy
- Chronic kidney disease
- Hyperuricemia
Also known as: familial juvenile hyperuricemic nephropathy 2