Conditions / Urinary
autosomal dominant tubulointerstitial kidney disease 6
info · Urinary
An autosomal dominant tubulointerstitial kidney disease characterized by the onset of slowly progressive chronic renal failure beginning in mid-to-late adulthood that has_material_basis_in heterozygous mutation in the APOA4 gene on chromosome 11q23.
Signs and symptoms
- Stage 5 chronic kidney disease
- Hypercholesterolemia
- Glomerular sclerosis
- Decreased glomerular filtration rate
- Chronic kidney disease
- Abnormal Bowman capsule morphology
- Hypertension
- Gout
- Renal tubular atrophy
- Glomerular basement membrane wrinkling