Conditions / Skin

autosomal recessive congenital ichthyosis 6

info · Skin · ICD-10: Q80.2

An autosomal recessive congenital ichthyosis characterized by generalized ichthyosis, hyperkeratosis, parakeratosis and moderate acanthosis that has_material_basis_in homozygous or compound heterozygous mutation in the NIPAL4 gene on chromosome 5q33.

Signs and symptoms

  • Palmoplantar keratoderma
  • Generalized ichthyosis
  • Epidermal acanthosis
  • Orthokeratosis
  • Dry skin
  • Scaling skin
  • Congenital nonbullous ichthyosiform erythroderma
  • Parakeratosis
  • Erythroderma
  • Hyperkeratosis

Also known as: ARCI6