autosomal recessive hyper-IgE syndrome 3 with recurrent infections

A hyper IgE syndrome that has_material_basis_in homozygous mutation in the ZNF341 gene on chromosome 20q11.

Signs and symptoms

• Recurrent skin infections
• Eczematoid dermatitis
• Increased circulating IgE concentration
• Mild intellectual disability
• Abnormality of the dentition
• Recurrent infections
• High palate
• Atopic dermatitis
• Bronchiectasis
• Recurrent mucocutaneous candidiasis

Also known as: hyper IgE recurrent infection syndrome 3