autosomal recessive intellectual developmental disorder 37

An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the ANK3 gene on chromosome 10q21.

Signs and symptoms

• Moderate intellectual disability
• Delayed speech and language development
• Sleep disturbance
• Hypotonia
• Global developmental delay
• Spasticity
• Intellectual disability
• Seizure
• Bruxism
• Generalized hypotonia