autosomal recessive intellectual developmental disorder 64

An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the LINGO1 gene on chromosome 15q24.

Signs and symptoms

• Global developmental delay
• Motor delay
• Severe intellectual disability
• Reduced social responsiveness
• Aggressive behavior
• Microcephaly
• Absent speech
• Hypertonia
• Feeding difficulties
• Slurred speech