autosomal recessive intellectual developmental disorder 69

An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the ZBTB11 gene on chromosome 3q12.

Signs and symptoms

• Moderate intellectual disability
• Delayed speech and language development
• Ataxia
• Drooling
• Spasticity
• Delayed ability to walk
• Microcephaly
• Facial hypotonia
• Dysarthria
• Global developmental delay

Also known as: neurodevelopmental disorder with progressive movement abnormalities, cognitive decline, and brain abnormalities