Conditions / Genetic

autosomal recessive limb-girdle muscular dystrophy type 2S

info · Genetic · ICD-10: G71.0

An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous mutation in the TRAPPC11 gene on chromosome 4q35.

Signs and symptoms

  • Elevated circulating creatine kinase activity
  • Limb-girdle muscular dystrophy
  • Intellectual disability
  • Truncal ataxia
  • Chorea
  • Hyperkinetic movements
  • Poor speech
  • Inability to walk
  • Strabismus
  • Dystonia

Also known as: LGMD2S; muscular dystrophy, limb-girdle, type 2S