Conditions / Syndrome
Buschke-Ollendorff syndrome
info · Syndrome
A syndrome characterized by multiple subcutaneous nevi or nodules and osteopoikilosis that has_material_basis_in heterozygous mutation in the LEMD3 gene on chromosome 12q14.3.
Signs and symptoms
- Osteopoikilosis
- Epidermal nevus
- Nevus
- Scoliosis
- Lower limb asymmetry
- Joint stiffness
- Flexion contracture
- Femoral osteopoikilosis
- Connective tissue nevi
- Melorheostosis
Also known as: BOS; dermatofibrosis lenticularis disseminata with osteopoikilosis; dermatoosteopoikilosis; disseminated dermatofibrosis with osteopoikilosis; osteopathia condensans disseminata