Cenani-Lenz syndactyly syndrome

A dysostosis characterized by syndactyly, malformation of the forearm and lower limb bones, renal hypoplasia or aplasia and that has_material_basis_in homozygous or compound heterozygous mutation in the LRP4 gene on chromosome 11p11.

Signs and symptoms

• Metacarpal synostosis
• Syndactyly
• Anonychia
• Prominent forehead
• Radioulnar synostosis
• Hypertelorism
• Hypoplasia of the ulna
• Malar flattening
• Hypoplasia of the radius
• Micrognathia

Also known as: syndactyly type 7