Conditions / Musculoskeletal

centronuclear myopathy X-linked

info · Musculoskeletal · ICD-10: G71.220

A centronuclear myopathy that has_material_basis_in X-linked inheritance of mutations in MTM1 on Xq28.

Signs and symptoms

  • Neonatal hypotonia
  • Low 1-minute APGAR score
  • Neonatal respiratory distress
  • Respiratory failure requiring assisted ventilation
  • Birth length greater than 97th percentile
  • Areflexia
  • Decreased fetal movement
  • Cryptorchidism
  • Facial palsy
  • Flexion contracture

Also known as: CNMX; MTM1; X-linked myotubular myopathy; XLCNM; XLMTM