Conditions / Musculoskeletal

Charcot-Marie-Tooth disease axonal type 2O

info · Musculoskeletal · ICD-10: G60.0

A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the DYNC1H1 gene on chromosome 14q32.

Signs and symptoms

  • Distal muscle weakness
  • Pes cavus
  • Motor delay
  • Hyporeflexia
  • Limb muscle weakness
  • Difficulty running
  • Peripheral neuropathy
  • Distal sensory impairment
  • Frequent falls
  • Delayed speech and language development

Also known as: Charcot-Marie-Tooth neuropathy axonal type 2O; autosomal dominant Charcot-Marie-Tooth disease type 2O; autosomal dominant axonal Charcot-Marie-Tooth disease type 2O