Conditions / Musculoskeletal

Charcot-Marie-Tooth disease axonal type 2P

info · Musculoskeletal · ICD-10: G60.0

A Charcot-Marie-Tooth disease type 2 that has_material_basis_in homozygous or heterozygous mutation in the LRSAM1 gene on chromosome 9q33.

Signs and symptoms

  • Hyporeflexia
  • Axonal degeneration/regeneration
  • Steppage gait
  • Decreased motor nerve conduction velocity
  • Pes cavus
  • Distal amyotrophy
  • Distal muscle weakness
  • Areflexia
  • Fasciculations
  • Axonal degeneration

Also known as: CMT2P; Charcot-Marie-Tooth disease type 2P; Charcot-Marie-Tooth neuropathy type 2P