Conditions / Musculoskeletal

Charcot-Marie-Tooth disease axonal type 2T

info · Musculoskeletal · ICD-10: G60.0

A Charcot-Marie-Tooth disease type 2 that has_material_basis_in homozygous or compound heterozygous mutation in the MME gene on chromosome 3q25.

Signs and symptoms

  • Hyporeflexia
  • Distal lower limb muscle weakness
  • Distal sensory impairment
  • Unsteady gait
  • Distal lower limb amyotrophy
  • Areflexia
  • Sensorimotor neuropathy
  • Foot dorsiflexor weakness
  • Dementia

Also known as: AR-CMT2T; CMT2T; Charcot-Marie-Tooth neuropathy type 2T; autosomal recessive axonal Charcot-Marie-Tooth disease type 2T