Conditions / Musculoskeletal

Charcot-Marie-Tooth disease type 2A1

info · Musculoskeletal · ICD-10: G60.0

A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the KIF1B gene on chromosome 1p36.

Signs and symptoms

  • Peripheral axonal neuropathy
  • Distal amyotrophy
  • Axonal degeneration/regeneration
  • Hyporeflexia
  • Facial palsy
  • Decreased motor nerve conduction velocity
  • Steppage gait
  • Pes cavus
  • Onion bulb formation
  • Areflexia

Also known as: CMT2A1; Charcot-Marie-Tooth disease neuronal type 2A1; Charcot-Marie-Tooth neuropathy type 2A1; HMSN IIA1; HMSN2A1