Conditions / Musculoskeletal

Charcot-Marie-Tooth disease type 2R

info · Musculoskeletal · ICD-10: G60.0

A Charcot-Marie-Tooth disease type 2 that has_material_basis_in homozygous or compound heterozygous mutation in the TRIM2 gene on chromosome 4q.

Signs and symptoms

  • Decreased motor nerve conduction velocity
  • Delayed ability to walk
  • Pes cavus
  • Hypotonia
  • Areflexia
  • Muscle weakness
  • Intrinsic hand muscle atrophy
  • Peripheral axonal neuropathy
  • Broad-based gait
  • Inability to walk

Also known as: CMT2R; Charcot-Marie-Tooth neuropathy type 2R; autosomal recessive axonal Charcot-Marie-Tooth disease type 2R