Conditions / Musculoskeletal

Charcot-Marie-Tooth disease type 4C

info · Musculoskeletal · ICD-10: G60.0

A Charcot-Marie-Tooth disease type 4 that has_material_basis_in homozygous or compound heterozygous mutation in the SH3TC2 gene.

Signs and symptoms

  • Distal muscle weakness
  • Distal sensory impairment
  • Distal amyotrophy
  • Scoliosis
  • Facial palsy
  • Decreased motor nerve conduction velocity
  • Delayed brainstem auditory evoked response conduction time
  • Motor delay
  • Abnormal cranial nerve morphology
  • Tongue atrophy

Also known as: CMT4C; Charcot-Marie-Tooth neuropathy type 4C; autosomal recessive demyelinating Charcot-Marie-Tooth disease type 4C