Conditions / Musculoskeletal

Charcot-Marie-Tooth disease type 4H

info · Musculoskeletal · ICD-10: G60.0

A Charcot-Marie-Tooth disease type 4 that has_material_basis_in mutations in the gene encoding frabin (FGD4).

Signs and symptoms

  • Hypoesthesia
  • Decreased motor nerve conduction velocity
  • Onion bulb formation
  • Areflexia
  • Motor delay
  • Decreased number of peripheral myelinated nerve fibers
  • Unsteady gait
  • Scoliosis
  • Talipes equinovarus
  • Hyporeflexia

Also known as: CMT4H; Charcot-Marie-Tooth neuropathy type 4H; autosomal recessive Charcot-Marie-Tooth disease type 4H; autosomal recessive demyelinating Charcot-Marie-Tooth disease type 4H