chromosome 16q22 deletion syndrome

A chromosomal deletion syndrome that has_material_basis_in an interstitial 16q22 deletion that is characterized by a failure to thrive in infancy, poor growth, delayed psychomotor development, hypotonia, and dysmorphic features, including large anterior fontan

A chromosomal deletion syndrome that has_material_basis_in an interstitial 16q22 deletion that is characterized by a failure to thrive in infancy, poor growth, delayed psychomotor development, hypotonia, and dysmorphic features, including large anterior fontanel, high forehead, diastasis of the cranial sutures, broad nasal bridge, hypertelorism, low-set abnormal ears, and short neck.

Signs and symptoms

• Failure to thrive
• Global developmental delay
• High forehead
• Growth delay
• Cryptorchidism
• Hypotonia
• Micrognathia
• Low-set ears
• Wide anterior fontanel
• Broad hallux