chromosome 4q21 deletion syndrome

A chromosomal deletion syndrome that has_material_basis_in deletion of the chromosome 4q21 region.

Signs and symptoms

• Severe short stature
• Long philtrum
• Delayed skeletal maturation
• Narrow mouth
• Global developmental delay
• Hypotonia
• Sensorineural hearing impairment
• Dolichocephaly
• Hypertelorism
• Broad forehead

Also known as: 4q21 microdeletion syndrome; monosomy 4q21