combined deficiency of vitamin K-dependent clotting factors 2

info · Genetic

A hereditary combined deficiency of vitamin K-dependent clotting factors that has_material_basis_in homozygous or compound heterozygous mutation in the VKORC1 gene on chromosome 16p11.2.

Signs and symptoms

Abnormal bleeding
Reduced factor IX activity
Reduced factor X activity
Reduced factor VII activity
Reduced prothrombin antigen

Also known as: VKCFD2