Conditions / Genetic

congenital disorder of glycosylation type IIc

info · Genetic · ICD-10: D71.1

A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the SLC35C1 gene on chromosome 11p11.2.

Signs and symptoms

  • Prominent fingertip pads
  • Short foot
  • Brachydactyly
  • Short stature
  • Coarse facial features
  • Severe intellectual disability
  • Bulbous nose
  • Delayed speech and language development
  • Global developmental delay
  • Autistic behavior

Also known as: CDG IIc; CDG2C; CDGIIc; Rambam-Hasharon syndrome