corticosterone methyloxidase deficiency 1

info · Endocrine

An adrenal gland disease that is characterized by excessive amounts of sodium released in the urine, along with insufficient release of potassium in the urine, usually beginning in the first few weeks of life.

Signs and symptoms

Vomiting
Hyperkalemia
Increased circulating renin concentration
Failure to thrive
Dehydration
Hyponatremia
Recurrent fever
Feeding difficulties in infancy
Decreased circulating aldosterone concentration
Hypotension

Also known as: aldosterone synthase deficiency