Crouzon syndrome

A craniosynostosis that involves premature fusion of certain skull bones. This early fusion prevents the skull from growing normally and affects the shape of the head and face. The disease is associated with mutations in the FGFR2 gene.

Signs and symptoms

• Coronal craniosynostosis
• Hypertelorism
• Deviated nasal septum
• Midface retrusion
• Conductive hearing impairment
• Convex nasal ridge
• Proptosis
• Dental crowding
• High palate
• Strabismus

Also known as: Craniofacial Dysostosis