Conditions / Genetic

dilated cardiomyopathy 2G

info ยท Genetic

A dilated cardiomyopathy that is characterized by early-onset severe dilated cardiomyopathy that progresses rapidly to heart failure in the neonatal period without evidence of intervening hypertrophy and that has_material_basis_in homozygous or compound hetero

A dilated cardiomyopathy that is characterized by early-onset severe dilated cardiomyopathy that progresses rapidly to heart failure in the neonatal period without evidence of intervening hypertrophy and that has_material_basis_in homozygous or compound heterozygous mutation in the LMOD2 gene on chromosome 7q31.

Signs and symptoms

  • Cerebral hemorrhage
  • Myofiber disarray
  • Paroxysmal ventricular tachycardia
  • Complete right bundle branch block
  • Monomorphic ventricular tachycardia
  • Severely reduced left ventricular ejection fraction
  • Left atrial enlargement
  • Tachycardia
  • Aortic regurgitation
  • Mitral regurgitation