distal arthrogryposis type 7

A distal arthrogryposis characterized by inability to open the mouth fully and pseudocamptodactyly that has_material_basis_in heterozygous mutation in the MYH8 gene on chromosome 17p13.1.

Signs and symptoms

• Trismus
• Microcephaly
• Talipes equinovarus
• Narrow mouth
• Distal arthrogryposis
• Joint contracture of the hand
• Foot joint contracture
• Mild microcephaly
• Absent antihelix
• Micrognathia

Also known as: DA7; Dutch-Kentucky syndrome; Hecht syndrome; Hecht-Beals syndrome; mouth, inability to completely open, and short finger-flexor tendons