Dubin-Johnson syndrome

A bilirubin metabolic disorder that involves elevated levels of unconjugated bilirubin without elevation of liver alanine transaminase and aspartate transaminase enzymes as a result of the deficient ability of hepatocytes to secrete conjugated bilirubin into t

A bilirubin metabolic disorder that involves elevated levels of unconjugated bilirubin without elevation of liver alanine transaminase and aspartate transaminase enzymes as a result of the deficient ability of hepatocytes to secrete conjugated bilirubin into the bile.

Signs and symptoms

• Conjugated hyperbilirubinemia
• Biliary tract abnormality
• Jaundice

Also known as: Dubin Johnson syndrome; chronic idiopathic jaundice