Conditions / Genetic

dystonia 23

info · Genetic · ICD-10: G24.8

A focal dystonia characterized by adult-onset cervical dystonia typically in the fourth or fifth decade of life that has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the CACNA1B gene on chromosome 9q34.

Signs and symptoms

  • Head tremor
  • Torticollis
  • Writer's cramp
  • Axial dystonia
  • Gait disturbance
  • Limb dystonia
  • Dysphonia
  • Myoclonus
  • Cerebellar atrophy
  • Cerebral cortical atrophy