Conditions / Genetic
epidermolytic hyperkeratosis 2B
info · Genetic
An epidermolytic hyperkeratosis that is characterized by generalized erythema, erosions, scaling, and easily breaking blisters that become less frequent later in life, while hyperkeratosis increases that has_material_basis_in homozygous mutation in the KRT10 g
An epidermolytic hyperkeratosis that is characterized by generalized erythema, erosions, scaling, and easily breaking blisters that become less frequent later in life, while hyperkeratosis increases that has_material_basis_in homozygous mutation in the KRT10 geneon chromosome 17q21.
Signs and symptoms
- Hypergranulosis
- Generalized hyperkeratosis
- Epidermal acanthosis
- Orthokeratosis
- Keratinocyte vacuolization
- Erythroderma
- Congenital nonbullous ichthyosiform erythroderma
- Cobblestone-like hyperkeratosis
- Abnormal blistering of the skin
- Hypernatremic dehydration
Also known as: autosomal recessive epidermolytic hyperkeratosis 2B