exfoliation syndrome

A phacogenic glaucoma that is characterized by open-angle glaucoma related to deposition of extracellular fibrillar material in anterior segment structures, which blocks aqueous fluid outflow, raises intraocular pressure, and leads to eventual optic nerve atro

A phacogenic glaucoma that is characterized by open-angle glaucoma related to deposition of extracellular fibrillar material in anterior segment structures, which blocks aqueous fluid outflow, raises intraocular pressure, and leads to eventual optic nerve atrophy and visual field loss. Exfoliation syndrome with symptoms of progressive decreased vision, especially peripheral vision. Exfoliation syndrome is caused by age-related deposition of fibrillar material in anterior segment structures.

Signs and symptoms

• Lens subluxation
• Anisocoria
• Phakodonesis
• Rigidity
• Iris hypoperfusion
• Retinal venous occlusion
• Mydriasis
• Pseudoexfoliation
• Pigment deposition in the trabecular meshwork
• Asymmetry of intraocular pressure

Also known as: Pseudoexfoliation glaucoma; Pseudoexfoliation syndrome