Conditions / Genetic
factor VII deficiency
info · Genetic · ICD-10: D68.2
A blood coagulation disease that is characterized by easy bleeding, with symptoms of epistaxis, bleeding of the gums, menorrhagia, and occasionally hemarthrosis, and has_material_basis_in autosomal recessive inheritance of mutation in the F7 gene, which encode
A blood coagulation disease that is characterized by easy bleeding, with symptoms of epistaxis, bleeding of the gums, menorrhagia, and occasionally hemarthrosis, and has_material_basis_in autosomal recessive inheritance of mutation in the F7 gene, which encodes coagulation factor VII, an important factor in the clotting cascade.
Signs and symptoms
- Menorrhagia
- Reduced factor VII activity
- Prolonged bleeding after dental extraction
- Joint hemorrhage
- Bruising susceptibility
- Epistaxis
- Abnormal bleeding
- Intramuscular hematoma
- Intracranial hemorrhage
Medications that may treat it
factor IX factor VII factor VIII
Also known as: deficiency, stable