factor XII deficiency

A blood coagulation disease that is characterized by prolonged PTT time without clinical symptoms, and has_material_basis_in a mutation in the F12 gene on chromosome 5q33.

Signs and symptoms

• Reduced factor XII activity
• Prolonged whole-blood clotting time
• Prolonged partial thromboplastin time

Also known as: Factor XII deficiency disease; Hageman Factor deficiency; deficiency, Hageman