factor XIII deficiency

A blood coagulation disease that is characterized by easy bleeding, with symptoms of prolonged umbilical cord bleeding, epistaxis, bleeding of the gums, menorrhagia, recurrent miscarriages, abnormal scar formation and wound healing, and hemarthrosis, and has_m

A blood coagulation disease that is characterized by easy bleeding, with symptoms of prolonged umbilical cord bleeding, epistaxis, bleeding of the gums, menorrhagia, recurrent miscarriages, abnormal scar formation and wound healing, and hemarthrosis, and has_material_basis_in autosomal recessive inheritance of mutation of the F13A1 or F13B gene, which encodes Factor XIII, formally known as fibrin stabilizing factor.

Signs and symptoms

• Abnormal bleeding
• Ecchymosis
• Abnormal umbilical stump bleeding
• Factor XIII subunit A deficiency
• Bruising susceptibility
• Reduced factor XIII activity
• Gingival bleeding
• Factor XIII subunit B deficiency
• Joint hemorrhage
• Intracranial hemorrhage

Also known as: Factor XIII deficiency disease; Hereditary factor XIII deficiency disease; deficiency, Laki-Lorand factor