familial adenomatous polyposis 4

info · Genetic

A familial adenomatous polyposis characterized by the development of multiple colonic adenomas in adulthood, often with progression to colorectal cancer and that has_material_basis_in compound heterozygous mutation in the MSH3 gene on chromosome 5q11.

Signs and symptoms

Adenomatous colonic polyposis
Breast intraductal papilloma
Uterine leiomyoma
Astrocytoma
Duodenal polyposis
Gastric adenocarcinoma
Renal cyst
Thyroid adenoma
Ovarian cyst