Conditions / Genetic
familial hyperaldosteronism III
info · Genetic
A familial hyperaldosteronism characterized by hypertension secondary to massive adrenal mineralocorticoid production that has_material_basis_in heterozygous mutation in the KCNJ5 gene on chromosome 11q24.
Signs and symptoms
- Increased circulating aldosterone concentration
- Decreased circulating renin concentration
- Hypertension
- Adrenal hyperplasia
- Hypokalemia
- Polydipsia
- Hypercalciuria
- Polyuria
- Metabolic acidosis