Conditions / Genetic

familial hypocalciuric hypercalcemia 3

info · Genetic · ICD-10: E83.5

A familial hypocalciuric hypercalcemia that has_material_basis_in heterozygous mutation in the AP2S1 gene on chromosome 19q13.

Signs and symptoms

  • Multiple lipomas
  • Bone pain
  • Hypercalcemia
  • Hypermagnesemia
  • Primary hyperparathyroidism
  • Parathormone-independent increased renal tubular calcium reabsorption
  • Osteomalacia
  • Chondrocalcinosis
  • Pancreatitis
  • Hypocalciuria

Also known as: FHH type 3; HHC3; familial hypocalciuric hypercalcemia type 3; hypocalciuric hypercalcemia type III