Conditions / Genetic

familial Mediterranean fever

info · Genetic · ICD-10: M04.1

An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.

Signs and symptoms

  • Polyarticular arthritis
  • Proteinuria
  • Arthralgia
  • Recurrent fever
  • Peritonitis
  • Pleuritis
  • Erysipelas
  • Abdominal pain
  • Episodic abdominal pain
  • Chest pain

Medications that may treat it

canakinumab colchicine

Also known as: FMF; benign paroxysmal peritonitis